MONITORING OF ANTICONVULSANT DRUG SIDE EFFECTS IN OUTPATIENTS WITH EPILEPSY
نویسندگان
چکیده
منابع مشابه
Rapid anticonvulsant monitoring in an epilepsy clinic.
The relevance of providing a rapid anticonvulsant monitoring service was assessed over a five year period at a paediatric epilepsy outpatient clinic. Altogether 481 drug assays were performed on 144 patients when considered clinically indicated. Drugs most frequently assayed were carbamazepine and sodium valproate, singly or in combination; sodium valproate, single or in combination; 90% of ass...
متن کاملAnticonvulsant effect and side effects
In a prospective study 44 children, aged 6 months to 5 years, admitted to hospital with febrile convulsions or epilepsy, were treated with diazepam in solution administered rectally during 59 generalised attacks. Rectal administration of diazepam was effective in the acute treatment of convulsions in 80% of cases. In 10% the treatment failed, whereas diazepam administered intravenously had prom...
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Introduction: Temporal lobe epilepsy(TLE) is a long lasting neurological disorder in which patients suffer from spontaneous seizures. New treatments with novel mechanisms of action are needed to help those patients whose seizures are resistant to available drugs. In this study, we investigated the possible neuroprotective effect of berberine in an intrahippocampal kainate model of TLE in rat. M...
متن کاملTherapeutic drug monitoring in epilepsy treatment
Drug monitoring as a means to adapt the dosage of antiepileptic drugs to achieve a particular concentration in blood is well documented. However, there are few studies showing the extent to which drug monitoring contributes toward greater effectiveness in epilepsy treatment as measured by better seizure control. The findings of SBU Alert show that there is currently poor* evidence to demonstrat...
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ABSTRACT Background and objective: Approximately 50 million people worldwide (1% of the world's population) suffer from epilepsy. Among 700 thousand people with epilepsy in Iran, 20% have refractory epilepsy. Accumulation of leukocytes in patients' brain parenchyma is thought to be related to different types of epilepsy. Recent clinical observat...
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2018
ISSN: 0975-7058
DOI: 10.22159/ijap.2018.v10s1.67